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Epanutin Capsule 100mg (Phenytoin) x100

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Epanutin is used for controlling generalized tonic-clonic seizures and partial seizures. It’s also manage status epilepticus, preventing seizure recurrence

23,000.00

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Availability: In Stock
SKU:EPA7328

Epanutin (Phenytoin) is a critical anticonvulsant medication designed to manage seizure disorders. This first-line antiepileptic drug provides reliable neurological protection, effectively controlling various types of epileptic seizures. Trusted by neurologists for its long-standing clinical efficacy in managing complex seizure conditions.

Uses

Epanutin is primarily prescribed for controlling generalized tonic-clonic seizures and partial seizures. It’s also utilized in managing status epilepticus, preventing seizure recurrence, and treating neurological conditions involving abnormal electrical brain activity.

Benefits

  • Effective seizure control
  • Rapid neurological stabilization
  • Long-term epilepsy management
  • Prevents seizure progression
  • Reduces seizure frequency
  • Suitable for various epilepsy types
  • Established safety profile
  • Consistent therapeutic outcomes
  • Multiple administration options
  • Cost-effective treatment

How It Works

Phenytoin stabilizes neuronal membranes by blocking sodium channels, preventing excessive electrical discharge in the brain. This mechanism reduces abnormal neuronal excitability, effectively preventing and controlling seizure activity.

Duration of Action

Onset of action: 1-2 hours

Peak plasma concentration: 4-8 hours

Half-life: 22-36 hours Steady-state levels achieved in 7-10 days

Therapeutic effects maintained with consistent dosing

Dosage

Adults: Initial dose 300mg daily, adjusted based on seizure control

Maintenance dose: 300-400mg daily in divided doses

Pediatric dosing: 4-8mg/kg/day

Individualized dosing based on patient response T

herapeutic drug monitoring recommended

Side Effects

Common effects include:

  • Gum hyperplasia
  • Neurological symptoms
  • Coordination difficulties
  • Skin rash
  • Cognitive changes Rare but serious side effects require immediate medical attention

Warning

Requires careful medical supervision. Potential for severe hypersensitivity reactions. Monitor blood levels regularly. Abrupt discontinuation may trigger seizures.

Pregnancy and Breastfeeding

Category D for pregnancy Potential risks to fetal development Limited transfer in breast milk Consultation with neurologist essential

Interactions

  • Reduces effectiveness of oral contraceptives
  • Interacts with multiple medications
  • Alters drug metabolism
  • Potential interactions with alcohol
  • May affect vitamin D absorption

Important Information

Consistent medication adherence critical. Regular neurological and blood monitoring required. Store at room temperature. Avoid sudden medication changes. Wear medical alert identification. Report any unusual neurological symptoms promptly.

Product Image Highlights

Epanutin Tablet
Epanutin
Epanutin 100mg
Epanutin Tablet 100mg

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Category Dosage Instructions
Seizures (Adults) Starting dose: 100 mg orally 3 times daily. Maintenance dose: 300–400 mg daily in divided doses. Adjust as needed.
Seizures (Children) Starting dose: 5 mg/kg/day in divided doses. Maintenance dose: 4–8 mg/kg/day. Do not exceed 300 mg daily.
Status Epilepticus (Adults) Loading dose: 10–15 mg/kg orally in divided doses. Maintenance: 100 mg orally 3 times daily.

How to Use:

  • Take with food to reduce stomach upset.
  • Do not crush or chew the capsule; swallow whole with water.
  • Ensure consistent timing for doses to maintain steady blood levels.
  • Avoid abrupt discontinuation without medical advice.

Important Information:

  • Common Side Effects: Drowsiness, dizziness, nausea, gum overgrowth, or unsteadiness.
  • Warnings:
    • Monitor blood levels regularly to avoid toxicity.
    • Use with caution in patients with liver or kidney impairment.
    • Avoid alcohol and grapefruit juice as they may affect phenytoin levels.
  • Interactions: Can interact with oral contraceptives, anticoagulants, and other anticonvulsants. Inform your doctor of all medications.
Contact a healthcare provider if side effects persist, seizures worsen, or signs of toxicity occur (e.g., confusion, ataxia, or rapid eye movements).

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